This subteam focuses computational methods in early-phase clinical development to efficiently and ethically generate robust evidence and insights. Some topics are dose-finding/optimization, quantitative decision making, master protocol and the utilization of multimodal data (biomarker, real-world data) to accelerate Go/No-Go decision making.
Heng Zhou (Merck) and Yingjie Qiu (University of Texas Southwestern Medical Center)
TBD